Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease.

Johannes HolleUwe QuerfeldMarietta KirchnerAlexandros AnninosJürgen OkunDaniela Thurn-ValsassinaAysun BayazitAna NiemirskaNur CanpolatIpek Kaplan BulutAli DuzovaAli AnaratRukshana ShroffYelda BilginerSalim CaliskanCengiz CandanJerome HarambatZeynep Birsin ÖzcakarOguz SoylemezogluSibylle TschumiSandra HabbigEbru YilmazAyse BalatAleksandra ZurowskaNilgun CakarBirgitta KranzPelin ErtanAnette MelkKarolis AzukaitisFranz Schaefer

Published in: Pediatric nephrology (Berlin, Germany) (2019)

Serum levels of gut-derived uremic toxins IS and pCS correlated inversely with eGFR in children. Only IS was significantly associated with surrogate markers of cardiovascular disease in this large pediatric CKD cohort.

Keyphrases

chronic kidney disease
cardiovascular disease
young adults
end stage renal disease
small cell lung cancer
type diabetes
epidermal growth factor receptor
peritoneal dialysis