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Regeneration of pulp-dentine complex-like tissue in a rat experimental model under an inflammatory microenvironment using high phosphorous-containing bioactive glasses.

J LiYahui WangYanmei Dong
Published in: International endodontic journal (2021)
The present preliminarily results demonstrated that the bioactive glass with a high proportion of phosphorus inhibited the inflammatory response and promoted the formation of a pulp-dentine complex in a rat experimental model. This study provides a foundation for the construction of materials with the dual functions of exerting anti-inflammatory effects and promoting tissue regeneration to meet the needs of dental pulp repair and regeneration.
Keyphrases
  • stem cells
  • inflammatory response
  • oxidative stress
  • wound healing
  • lipopolysaccharide induced
  • immune response
  • heavy metals