Epigenetic/genetic variations in CG-rich elements of immune-related genes contribute to food allergy development during childhood.

Maria KostaraVasiliki ChondrouVassilis FotopoulosArgyro SgourouSophia Tsabouri

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2022)

subpopulation generation to promote direct immune tolerance. Furthermore, clear evidence is provided for the underlying co-operation of genetic polymorphisms with epigenetic events, mainly at the CpG41 island of the HLA-DRB1 gene, which needs an extended investigation and elucidation.

Keyphrases

dna methylation
genome wide
copy number
gene expression
genome wide identification
young adults
transcription factor