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Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics.

Piao LuoJiayun ChenQian ZhangFei XiaChen WangYunmeng BaiHuan TangDandan LiuLiwei GuQingfeng DuWei XiaoChuanbin YangJi-Gang Wang
Published in: Precision clinical medicine (2022)
Collectively, our study provides novel knowledge of AAs-induced molecular characteristics of hepatotoxicity at a single-cell level and suggests future treatment options for AAs associated hepatotoxicity.
Keyphrases
  • single cell
  • drug induced
  • rna seq
  • high throughput
  • healthcare
  • high glucose
  • diabetic rats
  • endothelial cells
  • single molecule