Targeted exome analysis of Russian patients with hypertrophic cardiomyopathy.

Elena V FilatovaNatalia S KrylovaIvan N VlasovMaria S MaslovaNatalia G PoteshkinaPetr A SlominskyMaria I Shadrina

Published in: Molecular genetics & genomic medicine (2021)

The prevalence of individual pathogenic variants in HCM-related genes in Russian population appears to be lower than in general European population, which could be explained by ethnic features of Russian population, age characteristics of our sample, or unidentified pathogenic variants in genes previously not linked with HCM.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
copy number
risk factors
genome wide
heart failure
gene expression
dna methylation
genome wide identification
bioinformatics analysis
genome wide analysis