Influence of IL-β, IL-1RN, and TNF-α variants on the risk of acetylsalicylic acid-induced upper gastrointestinal bleeding: a case-control study.

Marcela Forgerini Cleslei Fernando Zanelli Sandro Roberto Valentini Patrícia de Carvalho Mastroianni

Published in: Einstein (Sao Paulo, Brazil) (2024)

This study aimed to explore pharmacogenomics biomarkers in low-dose acetylsalicylic acid users. Our data suggest that the presence of IL-1β, IL-1RN, and TNF-α variants was not associated with an increased risk of upper gastrointestinal bleeding.

Keyphrases

low dose
rheumatoid arthritis
copy number
dna methylation
big data
genome wide
clinical decision support