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Rate of Successful Extubation in Mechanically Ventilated Patients with Cirrhosis and Hepatic Coma.

Jeffrey T GibbsJeremy LouissaintElliot B Tapper
Published in: Digestive diseases and sciences (2022)
Mortality is high for all patients with cirrhosis requiring mechanical ventilation, including those intubated for grade 4 HE. Efforts to optimize the odds of successful extubation are urgently needed. Our findings suggest improved incidence of extubation associated with rifaximin administration in the first 24-h after intubation. Prospective, multi-center data to confirm these findings in this vulnerable population are warranted.
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