Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients.
Roderick A YaoOyediran AkinrinadeMarie ChaixSeema MitalPublished in: BMC medical genomics (2020)
High quality saliva samples that meet stringent QC criteria can be used for WGS when blood-derived DNA is not available or is not suitable. Saliva DNA provides an acceptable yield of SNV calls but has a lower yield for CNV calls compared to blood DNA.