[Effects of the Saponins from Panax japonicus on Intestinal Epithelial Tight Junction Proteins in Aging Rats].

Hai-ying WangYao-yan DunDing YuanMin LiuYu-hui GuoChang-cheng Zhang

Published in: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (2018)

The decreased level of intestinal tight junction proteins in the ileum of aging rats may be related to oxidative stress. Total saponins of Panax japonicus can up-regulate the level of intestinal tight junction proteins to improve the intestinal mucosal barrier dysfunction in the ileum of aging rat via reducing the levels of oxidative stress.

Keyphrases

oxidative stress
blood brain barrier
dna damage
diabetic rats
ischemia reperfusion injury
signaling pathway
ulcerative colitis