Proteomic biomarkers related to obesity in heart failure with reduced ejection fraction and their associations with outcome.
Teun B PetersenNavin SuthaharFolkert W AsselbergsMarie de BakkerK Martijn AkkerhuisAlina A ConstantinescuJan van RamshorstPeter D KatsikisPeter J van der SpekVictor A UmansRudolf A de BoerEric BoersmaDimitris RizopoulosIsabella KardysPublished in: Obesity (Silver Spring, Md.) (2024)
Patients with HFrEF and obesity show distinct proteomic profiles compared to patients with HFrEF without obesity. Obesity-related proteins are independently associated with HF outcome. These proteins carry potential to improve management of obesity-related HF and could be leads for future research.