Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use.

Mary Safy-KhanMaria J H de HairPaco M J WelsingJacob M van LaarJohannes W G Jacobsnull null

Published in: The Journal of rheumatology (2021)

Current smoking in patients with early RA significantly reduces the clinical effect of an MTX-based strategy, independent of whether concomitant prednisone is used. This effect is dose dependent.

Keyphrases

rheumatoid arthritis
smoking cessation
disease activity
ankylosing spondylitis
interstitial lung disease
cancer therapy
systemic sclerosis
drug delivery