Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine.

Ester De LeoAnna TarantaRoberto RasoElena PolishchukValentina D'OriaMarco PezzulloBianca Maria GoffredoSara CairoliFrancesco BellomoGiulia BattafaranoFrancesca Diomedi CamasseiAndrea Del FattoreRoman PolishchukFrancesco EmmaLaura Rita Rega

Published in: Human molecular genetics (2022)

These preclinical data indicate that genistein ameliorates kidney injury resulting from cystinosis with no side effects. Genistein therapy represents a potential treatment to improve the outcome for patients with cystinosis.

Keyphrases

mouse model
electronic health record
cell therapy
big data
combination therapy
machine learning
bone marrow
data analysis