CT-determined resectability of borderline resectable and unresectable pancreatic adenocarcinoma following FOLFIRINOX therapy.
Jong Keon JangJae Ho ByunJi Hun KangJung Hee SonJin Hee KimSeung Soo LeeHyoung Jung KimChanghoon YooKyu-Pyo KimSeung-Mo HongDong-Wan SeoSong Cheol KimMoon-Gyu LeePublished in: European radiology (2020)
• Margin-negative resection rate of pancreatic cancer following FOLFIRINOX therapy did not differ among each resectability (67-73%, p = 0.95) based on NCCN criteria or changes in resectability categories (56-77%, p = 0.39). • The sensitivity and specificity for margin-negative resection were 67% and 37% for resectability (resectable/borderline vs. unresectable) and 80% and 21% for changes in resectability (regression/stable vs. progression). • Low-contrast enhancement of soft tissue contacting artery (≤ 46.4 HU) was independently associated with margin-negative resection (p = 0.01).