Targeted biopsy of the prostate: does this result in improvement in detection of high-grade cancer or the occurrence of the Will Rogers phenomenon?
Edward J BassClément OrczykAlistair GreyAlex FreemanCharles JamesonShonit PunwaniNavin RamachandranClare AllenMark EmbertonHashim Uddin AhmedPublished in: BJU international (2019)
The use of targeted biopsy in men with impalpable cancer, ultimately upgraded one in five patients from favourable-intermediate- to unfavourable-intermediate-risk disease or worse. This has significant clinical implications for men considering active surveillance or radical treatment. Our risk calculators must now be validated using these data from targeted biopsy as the technique becomes widely adopted.
Keyphrases
- papillary thyroid
- high grade
- cancer therapy
- end stage renal disease
- ultrasound guided
- fine needle aspiration
- prostate cancer
- squamous cell
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk assessment
- peritoneal dialysis
- middle aged
- low grade
- prognostic factors
- electronic health record
- lymph node metastasis
- big data
- childhood cancer
- drug delivery
- sensitive detection
- patient reported