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The spectrum of cardiac abnormalities in patients with acromegaly: results from a case-control cardiac magnetic resonance study.

Dario De AlcubierreTiziana FeolaAlessia CozzolinoRiccardo PofiNicola GaleaCarlo CatalanoRenata Simona AuriemmaRosa PirchioRosario PivonelloAndrea M IsidoriElisa Giannetta
Published in: Pituitary (2024)
The CMR analysis reveals a cluster of biventricular structural and functional impairment in acromegaly, even when the biochemical control if achieved. These findings appear specifically triggered by the exposure to GH-IGF1 excess and show sex-related differences advocating a possible interaction with sex hormones in cardiac disease progression.
Keyphrases
  • magnetic resonance
  • left ventricular
  • growth hormone
  • case control
  • cell proliferation
  • contrast enhanced
  • atrial fibrillation