Gains in relative cortical area during growth and their relationship to nutrition, body size, and physical activity.
Libby W CowgillLesley HarringtonMarla MacKinnonHelen K KurkiPublished in: American journal of biological anthropology (2023)
The lack of a relationship between %CA and body mass suggests that %CA should not be used as an indicator of mechanical loading. The variation present across samples implies that appositional bone growth is affected by physiological stress in varying ways. Without a deeper understanding of what is "typical" for long bone development, it is impossible to draw conclusions about individual or population level health.