Effects of PEG-Linker Chain Length of Folate-Linked Liposomal Formulations on Targeting Ability and Antitumor Activity of Encapsulated Drug.

Chaemin LimYuseon ShinKioh KangPatihul HusniDayoon LeeSehwa LeeHan-Gon ChoiEun Seong LeeYu Seok Youn Kyung Taek Oh

Published in: International journal of nanomedicine (2023)

Our study suggests that as the length of PEG-linker increases, the tumor-targeting ability can be enhanced under in vivo conditions, which can lead to an increase in the antitumor activity of the encapsulated drug.

Keyphrases

drug delivery
cancer therapy
adverse drug
emergency department
electronic health record