Electronic health record biobank cohort recapitulates an association between the MUC5B promoter polymorphism and ARDS in critically ill adults.

Vern Eric Kerchberger Joel Brennan McNeil Neil S Zheng Diana Chang Adrienne G Randolph Angela J Rogers Julie A Bastarache QiPing Feng Wei-Qi Wei Lorraine B Ware

Published in: medRxiv : the preprint server for health sciences (2024)

and ARDS risk regardless of age and a novel association with oxygenation impairment. Our study highlights the potential for EHR biobanks to enable precision-medicine ARDS studies.

Keyphrases

electronic health record
acute respiratory distress syndrome
extracorporeal membrane oxygenation
mechanical ventilation
clinical decision support
dna methylation
adverse drug
gene expression
transcription factor
intensive care unit
risk assessment
blood flow
climate change