Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge.

Sandra Moreno Eva Calvo-Pinilla Stéphanie Devignot Friedemann Weber Javier Ortego Alejandro Brun

Published in: PLoS neglected tropical diseases (2020)

Though additional optimization will be needed to improve the efficacy data against BTV in sheep, our findings warrant further developments of attenuated RVFV as a dual vaccine platform carrying heterologous immune relevant antigens for ruminant diseases in RVF risk areas.

Keyphrases

dendritic cells
electronic health record
high throughput
big data
immune response
machine learning
saccharomyces cerevisiae