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Endometrial cancer with positive sentinel lymph nodes: pathologic characteristics of metastases as predictors of extent of lymphatic dissemination and prognosis.

Giorgia DinoiKhaled GhoniemYajue HuangValentina ZanfagninGiuseppe CucinellaCarrie L LangstraatGretchen E GlaserAmanika KumarAmy WeaverMichaela McGreeFrancesco FanfaniGiovanni ScambiaAndrea Mariani
Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2024)
Patients with positive SLN macrometastasis are independently associated with extensive lymphatic dissemination and distant recurrences. The risk of multiple positive SLNs increases with the extracapsular location of the SLN metastasis and with age. Independent uterine pathologic predictors of non-vaginal recurrence are non-endometrioid histology and cervical stromal invasion.
Keyphrases
  • lymph node
  • endometrial cancer
  • neoadjuvant chemotherapy
  • sentinel lymph node
  • locally advanced
  • bone marrow
  • cell migration
  • rectal cancer