Endocrine Disrupting Compounds (Nonylphenol and Bisphenol A)-Sources, Harmfulness and Laccase-Assisted Degradation in the Aquatic Environment.

Environmental pollution with organic substances has become one of the world's major problems. Although pollutants occur in the environment at concentrations ranging from nanograms to micrograms per liter, they can have a detrimental effect on species inhabiting aquatic environments. Endocrine disrupting compounds (EDCs) are a particularly dangerous group because they have estrogenic activity. Among EDCs, the alkylphenols commonly used in households deserve attention, from where they go to sewage treatment plants, and then to water reservoirs. New methods of wastewater treatment and removal of high concentrations of xenoestrogens from the aquatic environment are still being searched for. One promising approach is bioremediation, which uses living organisms such as fungi, bacteria, and plants to produce enzymes capable of breaking down organic pollutants. These enzymes include laccase, produced by white rot fungi. The ability of laccase to directly oxidize phenols and other aromatic compounds has become the focus of attention of researchers from around the world. Recent studies show the enormous potential of laccase application in processes such as detoxification and biodegradation of pollutants in natural and industrial wastes.