Dual-agent fluorescent labeling of soft-tissue sarcomas improves the contrast based upon targeting both interstitial and cellular components of the tumor milieu.

Hira S SardarQais ZaiXiaochun XuJason R GunnBrian W PogueKeith D PaulsenEric R HendersonKimberley S Samkoe

Published in: Journal of surgical oncology (2020)

Dual-agent imaging utilizing a single channel in a commercial fluorescence-guided imaging system tailored for IRDye 800CW is a promising method to increase tumor contrast in a clinical setting.

Keyphrases

high resolution
magnetic resonance
soft tissue
contrast enhanced
quantum dots
high grade
magnetic resonance imaging
cancer therapy
photodynamic therapy
energy transfer