Associations between Abdominal Trunk Muscle Weakness and Future Osteoporotic Vertebral Fracture in Middle-Aged and Older Adult Women: A Three-Year Prospective Longitudinal Cohort Study.
Satoshi KatoSatoru DemuraKazuya ShinmuraNoriaki YokogawaYuki KurokawaRyohei AnnenMotoya KobayashiYohei YamadaSatoshi NagataniHidenori MatsubaraTamon KabataHiroyuki TsuchiyaPublished in: Journal of clinical medicine (2022)
Potential risk factors associated with future osteoporotic vertebral fracture (OVF) were prospectively investigated in middle-aged and older adult women. We enrolled 197 female patients aged ≥50 years who were scheduled to undergo surgery for lower-extremity degenerative diseases. Patient anthropometric and muscle strength measurements, a bone mineral density measurement of the lumbar spine (L-BMD), and full-spine standing radiographs to examine the presence of old OVFs and spinopelvic sagittal parameters were obtained preoperatively. We evaluated 141 patients who underwent full-spine standing radiographs three years postoperatively to identify new OVFs. We excluded 54 patients who did not undergo a second radiographic examination and 2 with new traumatic OVFs. Univariate and multivariate analyses were performed to identify risk factors associated with new non-traumatic OVF occurrence. Ten (7.1%) patients developed new non-traumatic OVFs during the study period (fracture group). The fracture group had less abdominal trunk muscle strength, lower L-BMD, smaller sacral slopes, and larger pelvic tilt than the non-fracture group. The fracture group showed a higher prevalence of old OVFs preoperatively than the non-fracture group. Abdominal trunk muscle weakness, low L-BMD, and the presence of old OVFs were identified as significant risk factors for OVF occurrence. In middle-aged or older adult women, abdominal trunk muscle weakness, low L-BMD, and old OVFs were associated with future OVF.
Keyphrases
- bone mineral density
- end stage renal disease
- middle aged
- chronic kidney disease
- newly diagnosed
- body composition
- spinal cord injury
- prognostic factors
- physical activity
- postmenopausal women
- peritoneal dialysis
- risk assessment
- skeletal muscle
- polycystic ovary syndrome
- coronary artery disease
- type diabetes
- hip fracture
- metabolic syndrome
- young adults
- pregnancy outcomes
- atrial fibrillation
- risk factors
- acute coronary syndrome
- mass spectrometry
- patient reported