Etomidate protects retinal ganglion cells from hydrogen peroxide-induced injury via Nrf2/HO-1 pathway.
Xuan ZhaoDe-Gang FanXin-Chao ZhangSi-Wei YouFang KuangMing-Mei Wu
Published in: International journal of ophthalmology (2024)
. The effect of ET is dose-dependent with the greatest effect being at 10 µmol/L. ET plays an antioxidant role by inhibiting iNOS, up-regulating Nrf2/HO-1, decreasing the production of acrolein, and increasing the scavenge of acrolein.