Adiponectin profile at baseline is correlated to progression and severity of multiple sclerosis.

E SignorielloG LusR PolitoS CasertanoO ScudieroM ColettaM L MonacoF RossiE NigroAurora Daniele

Published in: European journal of neurology (2018)

This study demonstrated that adiponectin and its HMW oligomers are greatly involved in MS autoimmune disorder representing a potential biomarker to predict worse MS prognosis and severity. Further studies are required to clarify the molecular mechanisms underlying the properties of adiponectin and HMW oligomers in MS.

Keyphrases

multiple sclerosis
metabolic syndrome
mass spectrometry
insulin resistance
ms ms
white matter
drug induced