Modular networks and genomic variation during progression from stable angina pectoris through ischemic cardiomyopathy to chronic heart failure.

Lin ChenYa-Nan YuJun LiuYin-Ying ChenBo WangYi-Fei QiShuang GuanXi LiuBing LiYing-Ying ZhangYuanhui HuZhong Wang

Published in: Molecular medicine (Cambridge, Mass.) (2022)

The PDPMs analysis approach combined with genomic structural variation provides a new avenue for determining target associations contributing to disease progression and reveals that inflammation and angiogenesis may be important links among SAP, ICM and CHF progression.

Keyphrases

copy number
oxidative stress
coronary artery disease
heart failure
endothelial cells
percutaneous coronary intervention
vascular endothelial growth factor
ejection fraction
gene expression
brain injury
wound healing
atrial fibrillation
subarachnoid hemorrhage
data analysis