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PD-1 Involvement in Peripheral Blood CD8+ T Lymphocyte Dysfunction in Patients with Acute-on-chronic Liver Failure.

Xiaoshuang ZhouYidong LiYaqiu JiTian LiuNinghui ZhaoJiefeng HeJia Yao
Published in: Journal of clinical and translational hepatology (2021)
CD8+ T lymphocyte dysfunction is observed in patients with HBV-ACLF. PD-1-induced T lymphocyte dysfunction might involve glycolysis inhibition.
Keyphrases
  • peripheral blood
  • liver failure
  • hepatitis b virus
  • oxidative stress
  • diabetic rats
  • high glucose
  • drug induced
  • nk cells
  • stress induced