Intravenous Thrombolysis 4.5-9 Hours After Stroke Onset - a Cohort Study from the TRISP Collaboration.
Valerian L AltersbergerGerli SiboltLukas S EnzChristian HametnerJan F ScheitzHilde HenonGuido BigliardiDavide StramboNicolas Martinez-MajanderLotte J StolzeMirjam Rachel HeldnerIlaria GrisendiDejana R JovanovicYannick BejotAlessandro PezziniRonen R LekerGeorg KägiSusanne WegenerCarlo Walter CeredaGeorges NtaiosGian Marco De MarchisLeo H BonatiMarios PsychogiosPhilippe LyrerSilja RätyMarjaana TiainenAnke WoutersFrançois CaparrosMiriam HeyseHebun ErdurVisnja PadjenMarialuisa ZeddeMarcel ArnoldPaul J NederkoornPatrik MichelAndrea ZiniCharlotte CordonnierChristian H NoltePeter A RinglebSami CurtzeStefan T EngelterHenrik Gensickenull nullPublished in: Annals of neurology (2023)
This study showed no evidence in difference of sICH, poor outcome and mortality in selected stroke patients treated with IVT between >4.5-9 hours after stroke onset compared to those treated within 4.5 hours. Advanced neuroimaging for patient selection was associated with lower mortality. This article is protected by copyright. All rights reserved.