Arterial inflammation on [ 18 F]FDG PET/CT in melanoma patients treated with and without immune checkpoint inhibitors: CHECK-FLAME I.

Elissa A S PolomskiEllen W KapiteijnJulius C HeemelaarAnne V van der KolkTimo M KalisvaartAlina van de BurgtPetra Dibbets-SchneiderFloris H P van VeldenTom T P SeijkensJ Lauran StögerJ Wouter JukemaLioe-Fee de Geus-OeiM Louisa Antoni

Published in: Atherosclerosis (2024)

F]FDG PET/CT was observed in patients with advanced melanoma treated with ICIs only in the first six months after initiation of therapy, whereas no changes were observed in the control group. Moreover, arterial inflammation was mainly increased in patients without pre-existing inflammatory activity and with non-calcified lesions.

Keyphrases

oxidative stress
newly diagnosed
end stage renal disease
ejection fraction
prognostic factors
stem cells
mesenchymal stem cells
skin cancer
high resolution
basal cell carcinoma
simultaneous determination