Longitudinally Measured Fibrinolysis Factors are Strong Predictors of Clinical Outcome in Patients with Chronic Heart Failure: The Bio-SHiFT Study.
Victor J van den BergElke BouwensVictor A W M UmansMoniek P M de MaatOlivier C ManintveldKadir CaliskanAlina A ConstantinescuHenk MouthaanJan-Hein CornelSara BaartK Martijn AkkerhuisEric BoersmaIsabella KardysPublished in: Thrombosis and haemostasis (2019)
Longitudinally measured PAI-1, uPA, and suPAR are strongly associated with adverse cardiac events during the course of CHF. If future research confirms our results, these fibrinolytic factors may carry potential for improved, and personalized, heart failure surveillance and treatment monitoring.