Association between Polygenic Risk Scores for ADHD and Asthma: A Birth Cohort Investigation.

Douglas Teixeira LeffaBernardo HortaFernando C BarrosAna M B MenezesThais Martins-SilvaMara Helena HutzClaiton Henrique Dotto BauEugenio Horacio GrevetLuis Augusto RohdeLuciana Tovo-Rodrigues

Published in: Journal of attention disorders (2021)

Our results do not support a shared genetic background between both conditions. Findings should be viewed in light of important limitations, particularly the sample size and the self-reported asthma diagnosis. Studies in larger datasets are required to better explore the genetic overlap between adult ADHD and asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
attention deficit hyperactivity disorder
allergic rhinitis
autism spectrum disorder
working memory
genome wide
copy number
cystic fibrosis
air pollution
dna methylation
single cell