Standardization and validation of a high-efficiency liquid chromatography with a diode-array detector (HPLC-DAD) for voriconazole blood level determination.

Juan D Zapata Diego H Cáceres Luz E Cano Catalina De Bedout Sinar D Granada Tonny Williams Naranjo Preciado

Published in: Biomedica : revista del Instituto Nacional de Salud (2024)

The selectivity and chromatographic purity of the obtained signal, the detection limits, and the standardized quantification make this method an excellent tool for the therapeutic monitoring of patients treated with voriconazole.

Keyphrases

simultaneous determination
high efficiency
liquid chromatography
solid phase extraction
tandem mass spectrometry

high performance liquid chromatography
mass spectrometry
high resolution mass spectrometry
molecularly imprinted
ms ms

gas chromatography
high resolution
loop mediated isothermal amplification
real time pcr
label free

image quality
magnetic resonance imaging
computed tomography
structural basis