Peroxide-dependent oxidation reactions catalyzed by CYP191A1 from Mycobacterium smegmatis.

Hye-Yeong JoSun-Ha ParkThien-Kim LeSang Hoon MaDonghak KimTaeho AhnYoung Hee JoungChul-Ho Yun

Published in: Biotechnology letters (2017)

CYP191A1 preferentially catalyzes the peroxide-dependent oxidation of various substrates over the reductase-dependent reaction. Its peroxygenase activity may be used an effective biocatalytic tool to synthesize the metabolites of drugs.

Keyphrases

hydrogen peroxide
mycobacterium tuberculosis
ms ms
electron transfer
nitric oxide