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Angiotensin Deficient FVB/N Mice are Normotensive.

André Felipe RodriguesMihail TodirasFatimunnisa QadriNatalia AleninaMichael Bader
Published in: British journal of pharmacology (2023)
We describe a germline Agt-KO line that challenges all previous knowledge on BP regulation in mice with deletion of the classical RAS. This line may represent a model of drug-resistant hypertension because it lacks hypotension.
Keyphrases
  • drug resistant
  • wild type
  • multidrug resistant
  • acinetobacter baumannii
  • high fat diet induced
  • blood pressure
  • healthcare
  • angiotensin ii
  • pseudomonas aeruginosa
  • adipose tissue