Tachyphylaxis during treatment of exudative age-related macular degeneration with aflibercept.
Chikako HaraTaku WakabayashiYoko FukushimaKaori SayanagiRyo KawasakiShigeru SatoHirokazu SakaguchiKohji NishidaPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2019)
Tachyphylaxis occurs after repeated IVA injections in a minority of patients with AMD for a long term and is more likely to occur in eyes with lesions beneath the retinal pigment epithelium and no intraretinal edema. Treatment of AMD should be performed keeping this fact in mind, while considering the consecutive treatment.