Dietary non-starch polysaccharides impair immunity to enteric nematode infection.

Angela H ValenteKaren M R JensenLaura J MyhillLing ZhuCaroline M J MentzelLukasz KrychHenrik T SimonsenJosue L Castro-MejíaAlex GobbiKnud Erik Bach KnudsenDennis S NielsenStig M ThamsborgAndrew Richard Williams

Published in: BMC biology (2023)

Collectively, our data suggest that increasing levels of fermentable, non-starch polysaccharides in refined diets compromises immunity to helminth infection in mice. This diet-infection interaction may inform new strategies for manipulating the gut environment to promote resistance to enteric parasites.

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