Shenfu injection ameliorates endotoxemia-associated endothelial dysfunction and organ injury via inhibiting PI3K/Akt-mediated glycolysis.

Rui TianRanran LiYang ChenDi LiuYinjiaozhi LiShiyuan HeTingting PanHongping QuRuoming Tan

Published in: Journal of ethnopharmacology (2024)

Our findings revealed that SFI may improve microcirculation perfusion and endothelial function in sepsis via inhibiting PI3K/Akt-mediated glycolysis, providing theoretical evidence for the clinical application of SFI.

Keyphrases

pi k akt
signaling pathway
cell cycle arrest
cell proliferation
intensive care unit
acute kidney injury
single cell
cell death
septic shock
contrast enhanced