Association of the STAT4, CDKN1A, and IRF5 variants with risk of lupus nephritis and renal biopsy classification in patients in Vietnam.

Trung Dung NghiemGia Tuyen DoLong Hoang LuongQuy Linh NguyenHa Viet DangAnh Nguyen VietThuy Thu NguyenVan-Khanh TranThanh Van TaThinh Huy Tran

Published in: Molecular genetics & genomic medicine (2021)

This study investigates the relationship between STAT4, CDKN1A, and IRF5 gene and SLE in a Vietnamese patient population. Patients with the C allele (STAT4) in rs7582694 were associated with a more severe disease phenotype.

Keyphrases

cell proliferation
end stage renal disease
copy number
systemic lupus erythematosus
dendritic cells
ejection fraction
newly diagnosed
chronic kidney disease
machine learning
prognostic factors
rheumatoid arthritis
patient reported outcomes
dna methylation
ultrasound guided
disease activity