Green Synthesis, Characterization, and Biochemical Impacts of New Bioactive Isoxazoline-sulfonamides as Potential Insecticidal Agents against the Sphodroxia Maroccana Ley.

Novel isoxazolines containing sulfonamide moieties were designed, synthesized and confirmed by two single-crystal structures of 4e and 6q. Their bioassay results showed significant larvicidal activity with significant morphological changes in vivo. These results will lay the foundation for the further discovery and development of isoxazoline-sulfonamide derivatives as novel crop protection larvicides of cork oak. This article is protected by copyright. All rights reserved.