Kidney Clearance of Secretory Solutes Is Associated with Progression of CKD: The CRIC Study.

Yan ChenLeila R ZelnickKe WangAndrew N HoofnagleJessica O BeckerChi-Yuan HsuHarold I FeldmanRupal C MehtaJames P LashSushrut S WaikarTariq ShafiStephen L SeligerMichael G ShlipakMahboob RahmanBryan R Kestenbaumnull null

Published in: Journal of the American Society of Nephrology : JASN (2020)

We found lower kidney clearances of endogenous secretory solutes to be associated with CKD progression and all-cause mortality, independent of eGFR and albuminuria. This suggests that tubular clearance of secretory solutes provides additional information about kidney health beyond measurements of glomerular function alone.

Keyphrases

chronic kidney disease
small cell lung cancer
healthcare
public health
health information
mental health
tyrosine kinase
high glucose
social media