Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients.

Francesca BettelliDaniela ValleriniIvana LagrecaPatrizia BarozziGiovanni RivaVincenzo NasilloAmbra PaoliniRoberto D'AmicoFabio ForghieriMonica MorselliValeria PioliAndrea GilioliDavide GiustiAndrea MesserottiPaola BrescianiAngela CuoghiElisabetta ColaciRoberto MarascaLivio PaganoAnna CandoniJohan MaertensPierluigi VialeCristina MussiniRossella ManfrediniEnrico TagliaficoMario SartiTommaso TrentiRussell LewisPatrizia ComoliAlbino EccherMario LuppiLeonardo Potenza

Published in: PloS one (2024)

ELISpot shows promises in the diagnosis of IA and the possibility to use two distinct cut-offs with similar diagnostic performances according to patients' different pre-test probability of infection can widen its use in patients at risk.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
high throughput