Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms.

Xunwei DengJingyuan HouQiaoting DengZhixiong Zhong

Published in: World journal of surgical oncology (2020)

The results demonstrated that GSTP1 polymorphisms were useful predictors of severe events. Screening of single-nucleotide polymorphisms of GSTP1 in colorectal cancer patients before chemotherapy may help to realize personalized therapy.

Keyphrases

locally advanced
early onset
rectal cancer
radiation therapy
cell therapy