Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathway.

Ming LiuShaoxian WuHaoyu WuYou ZhouXinyu ZhangDawei ZhuJing Ting Jiang

Published in: Journal of translational medicine (2024)

Our findings highlight FDX1 as a potential tumor suppressor in LUAD, acting through modulation of the GPRIN2/PI3K signaling pathway. These results suggest FDX1 as a promising therapeutic target for LUAD treatment, warranting further investigation into its clinical relevance.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
induced apoptosis
cell proliferation
risk assessment
human health
endoplasmic reticulum stress