Basic fibroblast growth factor regulates phosphate/pyrophosphate regulatory genes in stem cells isolated from human exfoliated deciduous teeth.
Nunthawan NowwaroteWaleerat SukarawanPrasit PavasantBrian L FosterThanaphum OsathanonPublished in: Stem cell research & therapy (2018)
This study reveals for the first time the effects of bFGF on Pi/PPi regulators in SHEDs and implicates these factors in how bFGF directs osteo/odontogenic differentiation and mineralization by these cells.
Keyphrases
- stem cells
- induced apoptosis
- endothelial cells
- transcription factor
- cell cycle arrest
- genome wide
- induced pluripotent stem cells
- oxidative stress
- signaling pathway
- gene expression
- cell death
- endoplasmic reticulum stress
- cell therapy
- protein protein
- dna methylation
- genome wide identification
- cone beam computed tomography