Application of low-crystalline carbonate apatite granules in 2-stage sinus floor augmentation: a prospective clinical trial and histomorphometric evaluation.
Takayuki NakagawaKeiko KudohNaoyuki FukudaShohei KasugaiNoriko TachikawaKiyoshi KoyanoYasuyuki MatsushitaMasanori SasakiKunio IshikawaYouji MiyamotoPublished in: Journal of periodontal & implant science (2019)
In this first demonstration, low-crystalline CO3Ap granules showed excellent biocompatibility, and bone biopsy showed them to be replaced with bone in humans. CO3Ap granules are a useful and safe bone substitute for two-stage sinus floor augmentation.Trial Registration: ICTRP Identifier: JPRN-UMIN000019281.