Sex Differences in Adverse Drug Reactions of Metformin: A Longitudinal Survey Study.

Sieta T de Vries Petra Denig Corine Ekhart Peter G M Mol Eugene P van Puijenbroek

Published in: Drug safety (2021)

Sex differences in reported ADRs were seen in the first weeks after metformin initiation, whereas statistically significant differences in self-reported prescribed dosing were observed after several months. Patients, in particular women, might benefit from being prescribed lower metformin doses at treatment initiation.

Keyphrases

adverse drug
end stage renal disease
newly diagnosed
ejection fraction
prognostic factors
peritoneal dialysis
polycystic ovary syndrome
type diabetes
emergency department
electronic health record
pregnant women
patient reported
skeletal muscle
replacement therapy