Polyphosphate nanoparticles enhance the fibrin stabilization by histones more efficiently than linear polyphosphates.

Miklós LovasAnna Tanka-SalamonLászló BeinrohrIstván VoszkaLászló SzabóKinga MolnárKrasimir Kolev

Published in: PloS one (2022)

The interaction of PolyP with histone was a stronger modulator of fibrin formation and lysis than its interaction with DNA. In addition, the PolyP nanoparticles enhanced the thrombus stabilizing effects of histone more effectively than linear PolyP.

Keyphrases

dna methylation
platelet rich plasma
circulating tumor
cell free
gene expression
nucleic acid
circulating tumor cells