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Transient and reversible reduction of stratum corneum filaggrin degradation products after allergen challenge in experimentally mite-sensitised atopic dogs.

Thierry OlivryJudy S PapsNicolas Amalric
Published in: Veterinary dermatology (2021)
In this experimental model, a single epicutaneous allergen challenge led to a transient and reversible decrease in skin surface NMF and its components, and concentrations were negatively correlated with skin lesion scores. These observations suggest that some of the skin barrier anomalies seen in atopic dogs likely develop secondarily to the underlying cutaneous allergic inflammation.
Keyphrases
  • allergic rhinitis
  • atopic dermatitis
  • soft tissue
  • wound healing
  • oxidative stress
  • cerebral ischemia
  • subarachnoid hemorrhage