SynCardia Temporary Total Artificial Heart: Single-Center Experience at a Children's Hospital.
Tanya PerryDavid L S MoralesChet R VillaAlexis BenscoterKatrina FieldsAngela LortsPublished in: ASAIO journal (American Society for Artificial Internal Organs : 1992) (2022)
The SynCardia temporary total artificial heart (TAH-t) is a pneumatically driven pulsatile device that replaces a patient's ventricles and all four valves. It is now available in two sizes and can be used in patients with sufficient chest size as a bridge to transplant or destination therapy. We describe our experience at a children's hospital with the TAH-t. Seven patients implanted with a TAH-t at Cincinnati Children's Hospital Medical Center from November 2012 to March 2021 were included. Duration of support ranged from 10 to 414 days with a median of 27 days. There was a trend toward decreased time to extubation and intensive care unit (ICU) length of stay, with the three most recent patients being extubated on postoperative day 1. Seventy-one percent of the patients were successfully transplanted following their TAH-t placement. Children and young adults with transplant graft failure requiring durable, biventricular support with a TAH-t had superior outcomes (75% survival to retransplant) than previously described.
Keyphrases
- end stage renal disease
- intensive care unit
- newly diagnosed
- ejection fraction
- chronic kidney disease
- young adults
- peritoneal dialysis
- heart failure
- prognostic factors
- mechanical ventilation
- stem cells
- acute kidney injury
- aortic valve
- weight loss
- adverse drug
- extracorporeal membrane oxygenation
- ultrasound guided
- transcatheter aortic valve implantation
- aortic valve replacement
- aortic stenosis
- free survival