The Role of Cytokines in Acute and Chronic Postsurgical Pain in Pediatric Patients after Major Musculoskeletal Surgeries.

Vidya ChidambaranQing DuanValentina PilipenkoSusan M GlynnAlyssa SprolesLisa J MartinMichael J LacagninaChristopher D KingLili Ding

Published in: medRxiv : the preprint server for health sciences (2024)

We identified pro-inflammatory cytokines associated with increased acute postoperative pain and anti-inflammatory cytokines associated with lower CPSP risk, with potential to serve as predictive and prognostic biomarkers.

Keyphrases

postoperative pain
liver failure
respiratory failure
drug induced
chronic pain
aortic dissection
pain management
neuropathic pain
intensive care unit
spinal cord injury
spinal cord
climate change
mechanical ventilation